Derrida is typically taken to be the thinker most antithetical to Hegel, and deconstruction to be the philosophical antithesis to Hegel’s systematic rationality. While I do not dispute the accuracy of this perception, I argue in this paper that it does not offer an adequate or a complete picture. Specifically, much about Derrida and about deconstruction is more similar to Hegel than is typically realized. I argue that Derrida’s deconstruction shares a great affinity to the method of Hegel’s Phenomenology of (...) Spirit, so much so that we could identify and articulate a latent Hegelianism in Derrida’s approach. I begin with a description of Derrida’s own project, then offer something of an apologia for his work. Finally, I describe Hegel’s method of exposition [Darstellung] and compare it to deconstruction, pointing out the fundamental similarities between the two thinkers. (shrink)

Late in his life Leibniz famously recounted his philosophical conversion, at the young age of fifteen, from scholasticism to mechanism. Most Leibniz scholars have accepted Leibniz’s claim in this regard and have read his early works in philosophy and physics as various attempts to work out some variant of the mechanist position. However, Leibniz also makes it clear that he later came to realize the inadequacy of mechanism and, most would argue, this realization led him to reintroduce substantial form into (...) his ontological inventory in 1679. (shrink)

In his six 1983 lectures published under the title, Fearless Speech (2001), Michel Foucault developed the theme of free speech and its relation to frankness, truth-telling, criticism, and duty. Derived from the ancient Greek word parrhesia, Foucault's analysis of free speech is relevant to the mentoring of medical students. This is especially true given the educational and social need to transform future physicians into able citizens who practice a fearless freedom of expression on behalf of their patients, the public, the (...) medical profession, and themselves in the public and political arena. In this paper, we argue that Foucault's understanding of free speech, or parrhesia, should be read as an ethical response to the American Medical Association's recent educational effort, Initiative to Transform Medical Education (ITME): Recommendations for change in the system of medical education (2007). In this document, the American Medical Association identifies gaps in medical education, emphasizing the need to enhance health system safety and quality, to improve education in training institutions, and to address the inadequacy of physician preparedness in new content areas. These gaps, and their relationship to the ITME goal of promoting excellence in patient care by implementing reform in the US system of medical education, call for a serious consideration and use of Foucault's parrhesia in the way that medical students are trained and mentored. (shrink)

Levinas and other contemporary thinkers have claimed that the philosophy of "the other" provides a devastating critique of systematic rationality as such and of Hegel as a paradigm case thereof.The critique links an ethical moment and socio-political issues to a thorough-going critique of Hegelian metaphysics and the dialectical method. I articulate the meaning of alterity as a critique of Hegel through Levinas and Marx, and then discuss possible Hegelian responses to this criticism. I conclude that this critique of Hegel pertains (...) to the character of his final synthesis rather than to questions of difference and identity, and challenge the interpretation of Hegelian closure as the realization of eschatology. (shrink)

Bauer, Taub, and Parsi's review of an international sample of standards on informed consent, confidentiality, commercialization, and quality of research in tissue banking reveals that no clear national or international consensus exists for these issues. The authors' response to the lack of uniformity in the meaning, scope, and ethical significance of the policies they examined is to call for the creation of uniform ethical guidelines. This raises questions about whether harmonization should consist of voluntary international standards or international regulations that (...) include an official oversight mechanism and sanctions for noncompliance, and about who should participate in the harmonization process. Moreover, the normative assumptions and political dynamics that shape global policymaking need to be addressed. This commentary explores the policy implications and normative questions raised by the idea of international ethical guidelines for the use of biotechnologies and biotechnological resources such as stored samples of human tissue. (shrink)

In Capital as Organic Unity, Mark E. Meaney argues “that the doctrinal content of Marx’s Grundrisse is indebted for its logical form to Hegel’s exposition of logical categories as found in the Wissenschaft der Logik”. Meaney builds upon an important work by Hiroshi Uchida which had already explored Marx’s debt in the Grundrisse to Hegel’s Logic. But beyond Uchida’s claims, Meaney maps the entire structure of the Grundrisse onto the parallel movements of Hegel’s larger Science of Logic. Meany’s text contains (...) seven chapters. Besides the introduction and conclusion, one chapter discusses money as being, two discuss capital as essence or the essence of capital, and two more discuss the concept of capital in its objective, conceptual completeness. Capital is for Marx a concrete manifestation of Hegel’s objectification of the concept. (shrink)

BackgroundUnderstanding representations of disease in various art genres provides insights into how patients and health care providers view the diseases. It can also be used to enhance patient care and stimulate patient self-management.MethodsThis paper reviews how cardiovascular diseases are represented in novels, films, and paintings: myocardial infarction, aneurysm, hypertension, stroke, heart transplantation, Marfan’s disease, congestive heart failure. Various search systems and definitions were used to help identify sources of representations of different cardiovascular diseases. The representations of the different diseases were (...) considered separately. The Common Sense Model was used a theoretical model to outline illness perceptions and self-management in the various identified novels, films, and paintings.ResultsMyocardial infarction followed by stroke were the most frequently detailed diseases in all three art genres. This reflects their higher prevalence. Representations ranged from biomedical details through to social and psychological consequences of the diseases.ConclusionsArtistic representations of cardiovascular diseases reflect cognitions, emotions, and images of prevalent disease. These representations shape views and behaviour of ill and healthy persons regarding heart diseases. As these representations are amenable to change, they deserve further research, which may be instrumental in improving the quality of life of persons struck by cardiovascular diseases. Changing illness perceptions appears to be a method to improve self-management and thereby quality of life in patients with various cardiovascular diseases. (shrink)

Last year in June, British doctors went on strike for the first time since 1975. Amidst a global economic downturn and with many health systems struggling with reduced finances, around the world the issue of public health workers going on strike is a very real one. Almost all doctors will agree that we should always follow the law, but often the law is unclear or does not cover a particular case. Here we must appeal to ethical discussion. The General Medical (...) Council, in its key guidance document for practising doctors, Good Medical Practice, claims that ‘Good doctors make the care of their patients their first concern’. Is this true? And if so, how is this relevant to the issue of striking? One year on since the events, we carefully reflect and argue whether it was right for doctors to pursue strike action, and call for greater discussion of ethical issues such as the recent strikes, particularly among younger members of the profession. (shrink)

This paper explores how the Bayesian program benefits from allowing for objective chance as well as subjective degree of belief. It applies David Lewis’s Principal Principle and David Christensen’s principle of informed preference to defend Howard Raiffa’s appeal to preferences between reference lotteries and scaling lotteries to represent degrees of belief. It goes on to outline the role of objective lotteries in an application of rationality axioms equivalent to the existence of a utility assignment to represent preferences in Savage’s famous (...) omelet example of a rational choice problem. An example motivating causal decision theory illustrates the need for representing subjunctive dependencies to do justice to intuitive examples where epistemic and causal independence come apart. We argue to extend Lewis’s account of chance as a guide to epistemic probability to include De Finetti’s convergence results. We explore Diachronic Dutch book arguments as illustrating commitments for treating transitions as learning experiences. Finally, we explore implications for Martingale convergence results for motivating commitment to objective chances. (shrink)

Background: Legislation on physician-assisted suicide is being considered in a number of states since the passage of the Oregon Death With Dignity Act in 1994. Opinion assessment surveys have historically assessed particular subsets of physicians.Objective: To determine variables predictive of physicians’ opinions on PAS in a rural state, Vermont, USA.Design: Cross-sectional mailing survey.Participants: 1052 physicians licensed by the state of Vermont.Results: Of the respondents, 38.2% believed PAS should be legalised, 16.0% believed it should be prohibited and 26.0% believed it should (...) not be legislated. 15.7% were undecided. Males were more likely than females to favour legalisation . Physicians who did not care for patients through the end of life were significantly more likely to favour legalisation of PAS than physicians who do care for patients with terminal illness . 30% of the respondents had experienced a request for assistance with suicide.Conclusions: Vermont physicians’ opinions on the legalisation of PAS is sharply polarised. Patient autonomy was a factor strongly associated with opinions in favour of legalisation, whereas the sanctity of the doctor–patient relationship was strongly associated with opinions in favour of not legislating PAS. Those in favour of making PAS illegal overwhelmingly cited moral and ethical beliefs as factors in their opinion. Although opinions on legalisation appear to be based on firmly held beliefs, approximately half of Vermont physicians who responded to the survey agree that there is a need for more education in palliative care and pain management. (shrink)

We propose a model mechanism for the initiation and spatial positioning of teeth primordia in the alligator, Alligator mississippiensis. Detailed embryological studies by Westergaard and Ferguson have shown that jaw growth plays a crucial role in the developmental patterning of the tooth initiation process. Based on biological data we develop a dynamic patterning mechanism, which crucially includes domain growth. The mechanism can reproduce the spatial pattern development of the first seven teeth primordia in each half jaw of A. mississippiensis. The (...) results for the precise spatio-temporal sequence compare well with experiment. Simulation of the model also predicts that certain transplantations can alter the spatial sequence of teeth primordia initiation. (shrink)

Norms provide a valuable mechanism for establishing coherent cooperative behaviour in decentralised systems in which there is no central authority. One of the most influential formulations of norm emergence was proposed by Axelrod :1095–1111, 1986). This paper provides an empirical analysis of aspects of Axelrod’s approach, by exploring some of the key assumptions made in previous evaluations of the model. We explore the dynamics of norm emergence and the occurrence of norm collapse when applying the model over extended durations. It (...) is this phenomenon of norm collapse that can motivate the emergence of a central authority to enforce laws and so preserve the norms, rather than relying on individuals to punish defection. Our findings identify characteristics that significantly influence norm establishment using Axelrod’s formulation, but are likely to be of importance for norm establishment more generally. Moreover, Axelrod’s model suffers from significant limitations in assuming that private strategies of individuals are available to others, and that agents are omniscient in being aware of all norm violations and punishments. Because this is an unreasonable expectation, the approach does not lend itself to modelling real-world systems such as online networks or electronic markets. In response, the paper proposes alternatives to Axelrod’s model, by replacing the evolutionary approach, enabling agents to learn, and by restricting the metapunishment of agents to cases where the original defection is observed, in order to be able to apply the model to real-world domains. This work can also help explain the formation of a “social contract” to legitimate enforcement by a central authority. (shrink)

In this paper I reconstruct Hegel’s famous critique of irony by drawing on present-day vice epistemology. I argue that the categories of contemporary theories of epistemic vices are sufficient to classify a type of irony as a vicious stance. Yet they fail to grasp the property in virtue of which irony deserves criticism. I show that, for Hegel, this feature is intellectual pride. In the remainder of the paper, I specify the axiological, metaphysical, and epistemological background assumptions which guide the (...) self-assessment of proud persons according to Hegel. Finally, I throw some light on the theoretical presuppositions of Hegel’s account of irony and pride. (shrink)

Grodzinsky has argued that the traces deleted in Broca's aphasia are “phonetically silent but syntactically active” (sect. 2.). If we assume such traces to be visuospatial in nature, and adopt the term “overwriting” from the author's partial matching theory (1998), we can account for the errors made by Broca's aphasics in comprehending Grodzinsky's Examples (5a), (5b), and (6).

This chapter suggests that descriptive epidemiological studies like the Global Burden of Disease Study can usefully be divided into four tasks: describing individuals’ health states over time, assessing their health states under a range of counterfactual scenarios, summarizing the information collected, and then packaging it for presentation. The authors show that each of these tasks raises important and challenging ethical questions. They comment on some of the philosophical issues involved in measuring health states, attributing causes to health outcomes, choosing the (...) counterfactual against which to assess causes, aggregating and summarizing complex information across multiple domains, discounting, age-weighting, handling fetal deaths, measuring health inequalities, representing uncertainty, and assessing personal responsibility for health outcomes. (shrink)

The development of the typical cladomothallus of the red algae Antithaminion plumula (Ellis) Le Jolis [= Pterothamnion plumula (Ellis) Nägcli], (Rhodophyceae, Ceramiales) is simulated with the help of a formal language called L-systems. Two types of uniseriate filaments are distinguished: axial filaments of cladomes with indefinite growth and branching and pleuridia with definite growth and branching. The rythmical acropetal formation of secondary axes with basitonic arrangement contrasts with the intercalary basitonic formation of pleuridia, resulting in an acrotonic arrangement within an (...) axial segment. Five types of cells and two types of cell divisions intervene in the system. In addition, for the graphical representations, some morphological particularities of A. plumula are taken into account: the curvature of axial filaments, the extension of growth zones, variable cell generation times, and segment length variability along an axis. The incidence of these variables on the generated thallus form is emphasized, pointing to the singularities of A. plumula. (shrink)

Kovacs argues that honorary authorship and regarding each co-author of multi-authored papers as if they were sole authors when the performance of researchers is being evaluated by their publications mean that we should require authors to identify what proportion of each publication should be attributed to each co-author. Even if such attributions could be made reliably, such a change should not be made. Contributions to authorship cannot be validly quantified, and the relative merits of different publications are also neither equal (...) nor validly quantifiable. Research administrators need to recognise that whatever criteria they adopt to evaluate the performance of researchers, researchers will find a way to game the system in order to maximise their personal benefit. (shrink)

In this book G. W. Leibniz presents not only his reflections on predestination and election but also a more detailed account of the problem of evil than is found in any of his other works apart from the _Theodicy_. Surprisingly, his _Dissertation on Predestination and Grace_ has never before been published in any form. Michael J. Murray's project of translating, editing, and providing commentary for the volume will therefore attract great interest among scholars and students of Leibniz's philosophy and (...) theology. Leibniz addresses such topics as free will, moral responsibility, divine causation, justice, punishment, divine foreknowledge, and human freedom, revealing crucial aspects of the genesis of his mature metaphysics and the theological motivations behind it. (shrink)

ABSTRACT Written in late March 2020 in the early days of the U.S. coronavirus outbreak, this essay represents a contingent reflection on the American pandemic response, mourning in anticipation of what would soon surely unfold. I argue that the State's long-standing sacrificial economies have in this moment culminated in a suicidal State. The term is Foucault's, appearing in a controversial lecture on biopolitics, Nazism, and “biological racism.” Despite Foucault's problematic treatment of racism, I suggest that some aspects of this discourse (...) might nevertheless be apropos in our context. The U.S. pandemic response is racism's suicidal State legacy writ large: an extension and retooling of historically racist infrastructures deployed in racialized domains, but in this moment also across biosocial inequities and vulnerabilities marked by differential fungibilities other than race. (shrink)

Human beings, as a species, have two outstanding characteristics compared to all other species: the apparently enormous elaboration of our thought through language and symbolism, and the elaboration of our forms of social organization. The obvious question is whether these two characteristics are connected. ... Our view is that they are connected intimately. Thought and social organization are two aspects of the same larger phenomenon, or better the same larger bundle of phenomena. ... Here we bring the two streams of (...) analysis together, in what is at once an exposition of the basic structure of the systems of thought that organizations are built upon and, eo ipso, an exposition of the organizational basis and origin of human thinking as such. The resulting reconfiguring of questions, answers, and methods, we believe, cannot be described otherwise than as a new science and not just a new paradigm. (shrink)

Endo‐exonucleases from E. coli to man, although very different proteins, are multifunctional enzymes with similar enzymatic activities. They probably have two common but opposing biological roles. On the one hand, they promote survival of the organism by acting in recombination and recombinational DNA repair to diversify and help preserve the genome intact. On the other hand, they degrade the genomic DNA when it is damaged beyond repair. This ensures elimination of heavily mutagenized cells from the population.